Quick answer: GLP-1 medical weight loss at Prometheuz runs $179 to $339 per month. Cost depends on medication and plan length. Clinician review, medication management, and ongoing monitoring are included. Semaglutide starts at $249/mo, dropping to $179/mo annually. Tirzepatide starts at $339/mo, dropping to $269/mo annually. Oral semaglutide starts at $279/mo, dropping to $209/mo annually.
Prometheuz GLP-1 Pricing
Semaglutide Injectable
| Plan Monthly Cost Details |
| Monthly | $249/mo | No long-term commitment |
| 3-Month Plan | $219/mo | Save $90 total, billed $657 |
| 6-Month Plan | $199/mo | Save $300 total, billed $1,194 |
| 52-Week Plan | $179/mo | Save $910 total, billed $2,327 |
Tirzepatide Injectable
| Plan Monthly Cost Details |
| Monthly | $339/mo | No long-term commitment |
| 3-Month Plan | $309/mo | Save $90 total, billed $927 |
| 6-Month Plan | $289/mo | Save $300 total, billed $1,734 |
| 52-Week Plan | $269/mo | Save $910 total, billed $3,497 |
Oral Semaglutide
| Plan Monthly Cost Details |
| Monthly | $279/mo | No long-term commitment |
| 3-Month Plan | $259/mo | Save $60 total, billed $777 |
| 6-Month Plan | $239/mo | Save $240 total, billed $1,434 |
| 52-Week Plan | $209/mo | Save $910 total, billed $2,717 |
Every plan includes clinician review, medication management, and monitoring. Medication ships every 4 weeks. Louisiana allows branded medications only. See full GLP-1 details
Body Weight, BMI, and Fatty Liver Disease: What Your Healthcare Provider Reviews
GLP-1 medications aren't for every body weight. Most healthcare providers use body mass index (BMI) as a starting point. A BMI of 30 or higher generally qualifies on its own. A BMI of 27 or higher often qualifies too, if paired with a weight-related health condition.
Common qualifying conditions include pre diabetes, uncontrolled high blood pressure, sleep apnea, fatty liver disease, heart failure, chronic kidney disease, and peripheral artery disease affecting blocked arteries. Your health history and medical history both matter here. A healthcare provider reviews all of it before writing a personalized treatment plan for your weight loss journey, not just your weight.
GLP 1 Medications: How GLP 1s Work
GLP-1 medications, short for glucagon-like peptide-1, treat obesity and overweight by mimicking a gut hormone. This hormone slows digestion and helps you feel fuller longer. It also helps regulate blood sugar. That's the mechanism behind semaglutide, made by Novo Nordisk, and tirzepatide, made by Eli Lilly.
Semaglutide and tirzepatide are typically a once weekly injection. Oral semaglutide is a daily pill instead. Nausea is the most commonly reported side effect, especially early on. Most patients find it eases as the body adjusts.
What Affects GLP-1 Weight Loss Cost
Cost depends on a few clear factors. Here's what actually drives the price:
- Medication type. Tirzepatide costs more than semaglutide. It's a newer, dual-action compound.
- Delivery method. Oral semaglutide costs more than injectable. Oral formulations are more complex to compound.
- Plan length. Every medication gets cheaper per month the longer you commit. There's no penalty for staying month-to-month.
- Compounded vs. branded status. None of the three drugs covered here are FDA-approved products themselves. Branded versions like Wegovy and Zepbound are, at a different price point.
Compounded vs. Branded GLP-1: What You're Actually Paying For
Semaglutide and tirzepatide are compounded through a licensed 503A pharmacy here. They aren't FDA-approved products themselves. Branded Wegovy and Zepbound are FDA-approved, but full retail runs $900 to $1,640 per month without a discount program. Eli Lilly and Novo Nordisk both run direct-to-consumer programs instead. LillyDirect prices self-pay Zepbound at $349 to $599 a month. NovoCare Pharmacy prices self-pay Wegovy around $499 a month.
Compounding isn't a shortcut around approval. It's a different regulatory category entirely. Current FDA policy limits compounding to a documented individual clinical reason, not cost alone. Your clinician determines which path fits your case.
Is GLP-1 Weight Loss Covered by Insurance?
Sometimes, but insurance coverage is inconsistent. Whether your specific insurance plan covers weight-loss medication varies widely, even for branded, FDA-approved versions. When coverage exists, prior authorization is common and can take weeks, often with real out-of-pocket costs even after approval.
Prometheuz operates cash-pay. Pricing stays the same no matter your insurance situation. There's no prior authorization delay and no claim denial to navigate.
Medicare Drug Plan and Drug Coverage: The Medicare Bridge Program (GLP-1 Bridge Program)
Medicare Part D historically excluded weight loss drugs entirely. The Medicare GLP-1 Bridge Program changed that, running July 2026 through December 2027. Eligible beneficiaries on a Medicare drug plan or Medicare Advantage plan with drug coverage pay $50 a month for select GLP-1 medications, including Wegovy and Zepbound.
Eligibility requires a body mass index of 35 or higher alone, or 27 or higher with a condition like heart failure, uncontrolled high blood pressure, chronic kidney disease, or pre diabetes. Fatty liver disease, sleep apnea, and type 2 diabetes are excluded from this Medicare Bridge Program. Prometheuz operates cash-pay and doesn't bill Medicare, large employer plans, or any insurance provider.
How GLP-1 Cost Compares to Other Weight Loss Options
Bariatric surgery typically runs $15,000 to $25,000 upfront. Commercial weight-loss programs without medication often run $50 to $200 per month, with far more modest average results. GLP-1 medication sits in between: a real medical intervention, priced monthly instead of as one large expense.
At $179 to $339 per month, Prometheuz pricing lands within the typical range for legitimate telehealth GLP-1 providers. That range commonly runs $150 to $500 per month, depending on medication and provider.
What's Included in Every Plan
- Private health assessment, medical history, and health history review
- US-licensed clinician review and prescribing decision
- Personalized treatment plan for your weight loss journey
- Medication management and secure care messaging
- Follow-up visits and ongoing monitoring
- Labs where clinically indicated
Nothing here is billed as a separate line item.
GLP-1 Cost Over Time: Follow-Up Visits and Dose Changes
Getting started. Your first visit includes intake, clinician review, and a prescribing decision. This is built into your plan cost, no additional costs added later.
Ongoing. Follow-up visits continue for as long as you're on treatment. Dose changes happen during these visits, not as a separate charge. Many patients find this trade-off, more support in exchange for ongoing cost, worth it. Semaglutide drops from $249 to $179 per month on the annual plan, a real difference over a year.
See which GLP-1 option fits your goals
Frequently Asked Questions
Why does tirzepatide cost more than semaglutide?
Tirzepatide is a dual-action compound. It targets two receptor pathways instead of one. That makes it more complex and more expensive to compound.
Is oral semaglutide more expensive than the injectable version?
Yes. Oral formulations are harder to compound reliably. That extra complexity shows up in the price.
Does insurance cover GLP-1 weight loss medication?
Sometimes. Many plans exclude weight-loss medication entirely, even FDA-approved branded versions. Prometheuz is cash-pay, so pricing doesn't depend on your specific plan.
Is compounded GLP-1 the same as Wegovy or Zepbound?
Not exactly. Compounded semaglutide and tirzepatide use the same active ingredient. They aren't FDA-approved products themselves and are prescribed only when clinically appropriate.
Can I switch medications after starting?
Yes, based on your clinician's review of how you're responding. Your plan pricing adjusts to reflect whichever medication is actually prescribed.
Will my cost change once I start treatment?
Your plan rate stays fixed for its term. Dose changes happen during your regular follow-up visits, not as a separate charge.
What happens if I stop taking GLP-1 medication?
Appetite and body weight often trend back toward baseline. So many people underestimate this trade-off going in. Talk to your clinician first for more support before you stop.
Disclaimer
This content is for educational purposes only and does not replace medical advice. Compounded medications are not FDA-approved products. They are prepared by a licensed 503A pharmacy and prescribed only following an individualized clinician review. Not all patients will qualify. Not available in all states.
References
U.S. Food and Drug Administration. FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Loss. https://www.fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss
U.S. Food and Drug Administration. Human drug compounding. Updated February 2, 2026. https://www.fda.gov/drugs/guidance-compliance-regulatory-information/human-drug-compounding
Centers for Medicare & Medicaid Services. Medicare GLP-1 Bridge. https://www.cms.gov/medicare/coverage/prescription-drug-coverage/medicare-glp-1-bridge
