Quick answer: Peptide Therapy at Prometheuz runs $109 to $229 per month, depending on compound and plan length. Clinician review, medication management, and quarterly monitoring are included. NAD+ and Sermorelin start at $229/mo, dropping to $149/mo annually. B12-MIC starts at $145/mo, dropping to $109/mo annually. What's included matters as much as the number itself.
Prometheuz Peptide Therapy Pricing
NAD+
| Plan | Monthly Cost | Details |
|---|---|---|
| Monthly | $229/mo | No long-term commitment |
| 3-Month Plan | $179/mo | Save $150 total, billed $537 |
| 6-Month Plan | $159/mo | Save $420 total, billed $954 |
| 52-Week Plan | $149/mo | Save $1,040 total, billed $1,937 |
Sermorelin (Ages 25+ only)
| Plan | Monthly Cost | Details |
|---|---|---|
| Monthly | $229/mo | No long-term commitment |
| 3-Month Plan | $179/mo | Save $150 total, billed $537 |
| 6-Month Plan | $159/mo | Save $420 total, billed $954 |
| 52-Week Plan | $149/mo | Save $1,040 total, billed $1,937 |
B12-MIC
| Plan | Monthly Cost | Details |
|---|---|---|
| Monthly | $145/mo | No long-term commitment |
| 3-Month Plan | $129/mo | Save $48 total, billed $387 |
| 6-Month Plan | $119/mo | Save $156 total, billed $714 |
| 52-Week Plan | $109/mo | Save $468 total, billed $1,417 |
Every plan includes a US-licensed clinician review, medication management, secure care messaging, follow-up support, and quarterly monitoring. Compounds are prescribed only when clinically appropriate for your labs and goals, not selected off a menu. See full Peptide Therapy details
NAD IV Therapy vs. Injectable, Nasal, and Oral NAD+
NAD Infusion, IV Drip Sessions, and Multi-Session Packages: Typical Pricing
Most people researching NAD IV therapy costs picture an IV drip. NAD IV therapy is common at wellness spas and infusion centers. It delivers NAD+ through an IV infusion over one to several hours. The infusion rate gets adjusted based on how the body responds. Multi-session packages are typical. A single NAD infusion session runs $150 to $600 depending on the clinic and geographic location, plus a separate initial consultation cost. Whether NAD IV therapy is covered by insurance is also a possibility and varies too. Most NAD IV therapy sessions are cash-pay, same as Prometheuz.
Prometheuz doesn't offer NAD IV therapy. NAD+ here comes as an injectable via subcutaneous injections, a nasal spray, or an oral dropper. No infusion chair. No trained professionals monitoring an IV drip. No multi-session packages. Prometheuz is generally the more cost-effective option for ongoing personalized care.
Cellular Health and NAD Injections: How NAD+ Works
NAD+ is a coenzyme involved in energy production at the cellular level. That's part of why it's marketed around cellular health, mental clarity, brain fog reduction, and reduced fatigue. Patients notice increased energy at different rates. Most patients on NAD injections or other formats describe the effect as gradual, not immediate.
NAD injections and other formats are generally well tolerated, with typically mild side effects like injection site irritation. Patients report varying degrees of benefit. Many patients find oral supplements or oral supplementation options more convenient than an office visit, even though injectable NAD therapy is generally considered more directly absorbed.
Growth Hormone, Body Composition, and Energy Metabolism: What Sermorelin Targets
Sermorelin stimulates the pituitary gland to release more of the body's own human growth hormone, rather than supplying growth hormone directly. Treatment involves ongoing clinical guidance, not a one-time purchase. Patients typically pursue Sermorelin therapy for sleep quality, body composition, and energy metabolism goals. Some describe it in terms of fat metabolism, stress response support, and DNA repair-adjacent cellular processes tied to growth hormone signaling.
Whether Sermorelin pricing across typical ranges fits your goals depends on your health goals and baseline labs. Delivery method matters too. Injectable Sermorelin bypasses the absorption variability that comes with oral supplements passing through the digestive system.
How Peptide Therapy Cost Compares to HGH
Sermorelin gets compared to synthetic human growth hormone (HGH) often enough to address directly. HGH therapy typically runs $1,000 to $3,000 per month. That's several times the cost of Sermorelin, because it's a direct hormone replacement rather than a signal to your own pituitary gland.
At $149 to $229 per month, Prometheuz's Sermorelin pricing sits toward the accessible end of the broader market too. Industry-wide, Sermorelin pricing commonly runs $150 to $500 per month. That gap is one reason Sermorelin, not HGH, is the more common starting point for patients exploring growth hormone support.
What Affects Peptide Therapy Cost? Several Factors, Pricing Varies
Peptide pricing varies more between compounds than TRT or GLP-1 pricing does, because the three options target very different things:
- Which compound you're prescribed. NAD+ and Sermorelin cost more than B12-MIC, reflecting differences in the underlying compound and compounding complexity, not just markup.
- Plan length. Every compound gets cheaper per month the longer you commit, with no penalty for staying month-to-month.
- Monitoring requirements. Sermorelin's age restriction (25+) and quarterly monitoring cadence reflect a more involved clinical protocol than a B12-MIC shot, which is part of why pricing differs.
- Compounded vs. FDA-approved status. None of the three are FDA-approved for the uses described here. B12 itself is FDA-approved only for treating a diagnosed deficiency. That regulatory distinction affects both oversight and cost, covered in more detail below.
Compounded Peptides vs. FDA-Approved Medications
All three options are compounded through a licensed 503A pharmacy and prescribed off-label. This follows the same safety protocols regardless of which compound is FDA approved for a narrower use elsewhere. What differs between providers is whether that status gets disclosed clearly, and whether a licensed clinician actually reviews your labs before prescribing.
Insurance Coverage for Peptide Therapy
Generally, no. None of these three compounds are FDA-approved for the goals patients typically pursue them for: energy, sleep, recovery, general wellness. So insurance coverage is rare. Prior authorization is uncommon to get approved. B12 injections for a confirmed vitamin deficiency are the one exception, worth raising directly with your insurer.
Prometheuz operates cash-pay across all three compounds. Pricing stays the same regardless of your insurance situation. No prior authorization delays. No claim denials.
Clinical Oversight: Why It Matters More Than the Price Tag
A reputable clinic doesn't just sell a compound. It screens whether that compound is appropriate for you in the first place. Clinical oversight at Prometheuz means a licensed healthcare provider, not an intake form alone, reviews your medical history and health history before anything ships. That continues through quarterly follow-ups, not a single initial consultation.
Many patients comparing NAD IV therapy, injectable NAD+, or Sermorelin pricing across clinics focus on the number first. The trained medical professionals behind that number matter just as much. So does whether real medical oversight continues after the first purchase, for safety considerations over time.
What's Included in Every Plan
- Private health assessment and clinician intake
- Labs reviewed as clinically indicated (e.g., IGF-1 for Sermorelin candidates, B12 and homocysteine for B12-MIC candidates)
- US-licensed clinician review and prescribing decision
- Personalized treatment plan and medication management
- Secure care messaging with your care team
- Quarterly monitoring to track response and adjust as needed
Nothing here is billed as a separate line item.
Peptide Therapy Cost Over Time
Getting started. Your first month includes intake, a clinician review of your labs and goals, and a prescribing decision, whether that's NAD+, Sermorelin, B12-MIC, or a determination that none of the three fit your case.
Ongoing. Quarterly monitoring continues for as long as you're on treatment, built into your plan rate rather than billed per visit. The longer you commit upfront, the lower your effective monthly cost, most notably on NAD+ and Sermorelin, where the annual plan runs $80/month less than the monthly plan.
See if Peptide Therapy fits your labs and goals
Frequently Asked Questions
How much does peptide therapy cost per month?
At Prometheuz, NAD+ and Sermorelin run $149 to $229 per month depending on plan length. B12-MIC runs $109 to $145 per month. Clinician review, medication management, and quarterly monitoring are included in every plan.
Why does Sermorelin cost the same as NAD+ but more than B12-MIC?
Sermorelin and NAD+ involve a more complex compound and a more involved monitoring protocol (Sermorelin specifically requires patients to be 25 or older). B12-MIC is a simpler formulation with a lighter monitoring requirement, which is reflected in its lower price.
Is peptide therapy covered by insurance?
Rarely. NAD+ and Sermorelin aren't FDA-approved for wellness-related uses, so insurance coverage is uncommon. B12 injections for a confirmed deficiency occasionally have a coverage pathway, worth checking directly with your insurer.
Can I switch between compounds?
Switching is a conversation for your clinician, based on your labs and how you're responding, not a self-directed change. Your plan pricing would adjust to reflect whichever compound is actually prescribed.
Is a cheaper peptide provider actually cheaper?
Not always. Check whether clinician review, labs, and quarterly monitoring are included in the advertised price, or billed separately afterward. A lower headline number with itemized add-ons can end up costing more overall.
Do I need labs before starting peptide therapy?
Labs are reviewed as clinically indicated, for example IGF-1 for Sermorelin candidates or B12 and homocysteine levels for B12-MIC candidates, and are part of your plan rather than a separate charge.
Disclaimer
This content is for educational purposes only and does not replace medical advice. NAD+ and Sermorelin are not FDA-approved for the uses described. Compounded medications are prepared by a licensed 503A pharmacy and prescribed only following an individualized clinician review. Not all patients will qualify. Sermorelin is available only to patients aged 25 and older.
References
U.S. Food and Drug Administration. Determination that GEREF (Sermorelin Acetate) Injection was not withdrawn from sale for reasons of safety or effectiveness. Federal Register. 2013. https://www.federalregister.gov/documents/2013/03/04/2013-04827/determination-that-geref-sermorelin-acetate-injection-05-milligrams-basevial-and-10-milligrams
National Institutes of Health, Office of Dietary Supplements. Vitamin B12 Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
Gallagher C, Emmanuel OO. NAD+ supplementation for anti-aging and wellness: a PRISMA-guided systematic review of preclinical and clinical evidence. Ageing Res Rev. 2026;116:103057. https://www.sciencedirect.com/science/article/pii/S1568163726000498
Using HSA and FSA Funds for Peptide Therapy: What Qualifies, How to Document It, and What to Avoid. Meto. 2026. https://meto.co/blog/hsa-fsa-peptide-therapy-2026
